Stem cell injections for severe GVHD dry eye
Part of Eyes & vision, Immune system & allergy clinical trials.
This trial tests whether stem cell injections into the eye can help people with severe dry eye caused by graft-versus-host disease that hasn't gotten better with standard treatments. It aims to reduce eye pain and improve vision.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You have severe chronic GVHD that affects both eyes for more than 3 months and causes intense discomfort and damage to the cornea.
- You have already tried eye drops made from blood products, insulin, or cyclosporine/tacrolimus for at least 3 months without success.
- You use lubricating eye drops at least 4 times a day but still have severe eye symptoms.
- If you use steroid eye drops, the dose must have been stable for at least 1 month.
- You are not pregnant or breastfeeding, and you agree to use contraception during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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