Comparing platelet-rich fibrin vs steroid injections for knee arthritis
Treatments studied
Part of Bones, joints & muscles clinical trials.
This study compares two types of knee injections for people with mild to moderate knee arthritis: one using a concentration of your own blood cells (platelet-rich fibrin) that may help repair tissue, and the other using a standard corticosteroid to reduce inflammation. The goal is to see which works better for easing pain and improving function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 50 years old.
- You must have mild or moderate knee arthritis (grade 2 or 3) confirmed by X-ray.
- Your knee pain must have persisted (score above 40/100) for at least a week in the last month, even after trying non-surgical treatments for 3 months or more.
- You should not have had a steroid or hyaluronic acid injection in your knee within the last 6 months.
- You cannot be a smoker, have poorly controlled diabetes, kidney disease, bleeding problems, severe heart disease, or an active infection or cancer, among other conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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