Clin2
NCT06912152Worth exploringRecruiting

Testing MT027 for advanced belly-lining cancers

B7-H3-positive Advanced Malignant Solid Tumors Advanced Primary Peritoneal Tumors or Secondary Abdominal Metastatic Malignant Solid Tumors

Part of Cancer clinical trials.

This trial tests an experimental intraperitoneal therapy (MT027) for people whose advanced solid tumors have spread to the lining of the belly (peritoneum) and haven't responded to standard treatments. It aims to see if this new approach can help shrink or control the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
12 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You must be between 18 and 70 years old.
  • Your cancer must have spread to the lining of your belly (peritoneal cavity) and be confirmed by a biopsy or scan.
  • You must have tried at least 2 standard treatments and they didn't work, or no standard treatment is available for your cancer.
  • A sample of your tumor or belly fluid must test positive for a marker called B7-H3.
  • You should be in fairly good health, able to walk and take care of yourself (ECOG score 0-2), with an expected survival of at least 3 months.
  • You need to have decent blood counts, liver and kidney function, and be willing to use birth control during and for 6 months after treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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