Venlafaxine to prevent nerve pain after shingles
Treatments studied
Part of Brain & nervous system, Infections, Pain clinical trials.
This trial tests whether the drug venlafaxine, usually used for depression, can help prevent long-term nerve pain (postherpetic neuralgia) after a shingles infection. If you are currently experiencing shingles pain, joining this study might reduce your chances of developing chronic pain later.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have a shingles rash that started less than 30 days ago.
- Your current pain from shingles is at least a 4 on a 0-to-10 scale.
- You do not have shingles in your head, neck, or eyes.
- You are not pregnant or breastfeeding.
- You do not have other major medical conditions like cancer, organ transplant, or autoimmune disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether adding esketamine to two standard pain medicines (pregabalin and duloxetine) can better treat nerve pain from shingles that persists for months. It's for people whose pain hasn't improved enough with pregabalin alone.
This trial tests a new medicine called crisugabalin to see if it safely reduces shingles pain. It may help if you have moderate to severe pain from a shingles rash that started less than 3 months ago.
This study tests whether adding a medicine called esketamine to a standard nerve block procedure can improve pain relief for people with shingles-related nerve pain. If you have had shingles pain for less than 3 months, this might help reduce pain and prevent long-term discomfort.
This study tests a combination of two treatments for long-term nerve pain after shingles: a medication called esketamine and a nerve block (pulsed radiofrequency) applied to the affected spinal nerves. The goal is to see if this combination relieves the burning or shooting pain better than the nerve block alone.
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