Esketamine with pulsed radiofrequency for shingles-related face pain
Treatments studied
Part of Brain & nervous system, Infections, Mouth & dental, Skin clinical trials.
This trial tests whether adding esketamine (a medicine related to ketamine) to a standard nerve treatment (pulsed radiofrequency) can better relieve face pain caused by shingles. It may help if you have ongoing, moderate-to-severe pain in your face or scalp.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are older than 18
- You had shingles (herpes zoster) in the past 3 months
- Your pain is in the face or scalp, where the trigeminal nerve works
- Your pain is a 4 or higher on a 0-10 scale even with pain medicine
- You plan to get a procedure called CT-guided pulsed radiofrequency (PRF) on a nerve bundle in your face (the Gasserian ganglion)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether adding esketamine (a fast-acting pain medicine) to a standard nerve treatment called pulse radiofrequency (PRF) can better relieve lasting facial pain from shingles. It may help people who still have pain in the face or head after shingles.
This study tests a combination of a nasal spray medicine (esketamine) and a nerve treatment (pulsed radiofrequency) to reduce severe shingles pain. It may help people who have had shingles pain for less than 3 months and are already scheduled for the nerve procedure.
This study tests a combination of a nasal spray medicine (esketamine) and a minimally invasive procedure (pulsed radiofrequency treatment of the nerve root) to treat long-lasting pain from shingles (postherpetic neuralgia). It is for adults with moderate to severe pain that has persisted for more than 3 months.
This trial tests whether adding esketamine to two standard pain medicines (pregabalin and duloxetine) can better treat nerve pain from shingles that persists for months. It's for people whose pain hasn't improved enough with pregabalin alone.
This trial tests a new pain medication called tulodesvenlafaxine for people with shingles-related pain. It may help if you have moderate to severe pain that started within the last 90 days.
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