Loncastuximab tesirine for lymphoma after CAR-T therapy
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests a drug called loncastuximab tesirine for people with diffuse large B-cell lymphoma or high-grade B-cell lymphoma that has come back or not responded after CAR-T cell therapy. It aims to see if the drug can help when other treatments have stopped working.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have diffuse large B-cell lymphoma or high-grade B-cell lymphoma that did not respond to or came back after CAR-T therapy.
- You are able to perform daily activities with little to no help (ECOG score 0-2).
- Your cancer is measurable on a scan (PET/CT or MRI).
- Your heart, kidneys, liver, and lungs are working well enough, and your blood counts are within safe ranges.
- You are not pregnant or breastfeeding, and you agree to use birth control if needed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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