Probiotics for joint infection surgery
Part of Bones, joints & muscles, Immune system & allergy, Infections clinical trials.
This study tests if taking probiotics before and after surgery can help your immune system fight infection in a hip or knee replacement. You would be given a probiotic or a placebo alongside your standard treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 90 years old.
- You have a confirmed infection in a hip or knee replacement.
- You are scheduled for surgery that involves cleaning the infection while keeping the implant, or replacing the joint in one or two stages.
- You do not have serious gut problems like inflammatory bowel disease or a history of bowel surgery.
- You do not have a weakened immune system (e.g., from HIV, cancer treatment, or long-term steroids).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether taking probiotics can help prevent another infection in people who have had a hip or knee replacement that became infected. If you are scheduled for revision surgery due to an infection, this study may be a good fit.
This trial tests a new medicine called PLG0206 to help prevent a knee infection from coming back after a procedure to clean the joint while keeping the artificial knee in place. If you qualify, you'll receive the study medicine or a placebo along with standard antibiotics.
This study follows people who have an infection around a hip, knee, or shoulder implant (prosthesis). It uses standard infection tests (like cultures and blood tests) to confirm the diagnosis and better understand this problem after surgery.
This study looks at whether taking probiotics alongside antibiotics before and after surgery can help keep your gut bacteria healthy. It is for healthy adults having minor orthopedic surgery, like carpal tunnel or knee arthroscopy.
This trial compares taking antibiotics by mouth versus through an IV line for people who have an infection in their hip or knee replacement. The goal is to see if oral antibiotics work just as well as IV antibiotics after surgery to clean the infection.
This trial studies whether giving antibiotics before and/or after surgery can lower the chance of a serious joint infection after elective hip or knee replacement. It’s aimed at people at higher risk for infection.
Hear when a new Prosthetic Joint Infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.