Clin2
NCT06931717Possibly a fitRecruiting

Immunotherapy after lung cancer surgery for those not getting chemo

Non-Small Cell Lung Cancer

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests if the drug cemiplimab can prevent non-small cell lung cancer from coming back after surgery. It's for people whose tumors have PD-L1 levels of at least 1% and who are not receiving standard chemotherapy after surgery.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
390 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You had surgery to remove stage 2 or 3 non-small cell lung cancer, and the surgeon got all the cancer out.
  • Your tumor has a protein called PD-L1 at a level of 1% or higher.
  • You are not getting chemotherapy after surgery, either because you chose not to or your doctor said you're not healthy enough for it.
  • You are at least 18 years old and have recovered from your surgery.
  • Your cancer does not have an EGFR mutation or ALK rearrangement.
  • You are not pregnant, and you agree to use effective birth control during the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07720167Not yet recruiting· Phase 2
Cemiplimab for early stage non-small cell lung cancer before surgery

This trial tests giving Cemiplimab, an immunotherapy drug that helps your immune system fight cancer, before surgery to remove early stage non-small cell lung cancer. It aims to see if this approach can improve outcomes for people with small tumors that are more aggressive based on PET scan activity or cell appearance.

Charleston, South Carolina
NCT06743581Recruiting
Cemiplimab and dupilumab before lung cancer surgery

This study tests two drugs, cemiplimab and dupilumab, given before surgery for early-stage non-small cell lung cancer. The goal is to see if these drugs can shrink the tumor and improve outcomes.

Montreal, Quebec
NCT06088771Recruiting· Phase 1/Phase 2
Study of dupilumab and cemiplimab before lung cancer surgery

This study tests two drugs, dupilumab and cemiplimab, given before surgery for early-stage lung cancer. The goal is to see if these immune-boosting medicines can shrink the tumor and improve outcomes.

New York, New York
NCT07450183Not yet recruiting· Phase 2
Cemiplimab before and after surgery for early-stage lung cancer with high PD-L1

This trial tests if the immunotherapy drug cemiplimab, given before and after surgery, can help treat early-stage non-small cell lung cancer that has high levels of a protein called PD-L1. If you have stage II or IIIA lung cancer that can be surgically removed and your tumor has PD-L1 expression of 50% or more, you may be eligible.

Detroit, Michigan
NCT07746388Not yet recruiting· Phase 2
Adaptive chemo for high PD-L1, resectable lung cancer

This trial tests a personalized chemotherapy approach for people with early-stage (stage II–IIIB) non-small cell lung cancer that can be removed with surgery. It uses the tumor's PD-L1 level (a marker that helps the immune system attack cancer) to guide treatment before surgery, aiming to improve outcomes.

NCT06449313Recruiting· Phase 2
Immunotherapy before lung cancer surgery for stage 3 disease

This trial tests whether giving chemotherapy plus immunotherapy before surgery can help shrink stage 3 lung cancer and improve outcomes. The goal is to make the tumor easier to remove and possibly lower the chance of it coming back.

Washington D.C., District of Columbia

Hear when a new Non Small Cell Lung Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.