Starting semaglutide again after weight-loss surgery in teens
Treatments studied
Part of Hormones & metabolism clinical trials.
This trial tests if restarting semaglutide (a weekly injection for weight loss) soon after sleeve gastrectomy helps teens with severe obesity keep losing weight. It is for patients who were already taking semaglutide before their surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 12 and 18 years old.
- You have reached Tanner stage 3 puberty or higher.
- You have severe obesity (BMI over 35, or BMI at least 140% of the 95th percentile).
- You are planning to have weight-loss surgery at Children's Hospital Los Angeles.
- You are already taking semaglutide 2.4 mg once a week as part of your regular care, before surgery.
- You are willing to have blood tests and allow your medical information to be entered into a study database.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study looks at how teenagers and young adults respond to weight-loss surgery (sleeve gastrectomy) and whether adding a medication called semaglutide can help improve weight loss. It has two parts: first observing how surgery affects you, then testing if semaglutide helps those who didn't lose enough weight after surgery.
This study tests whether taking semaglutide (a once-weekly injection that helps control appetite and blood sugar) before and after a second weight-loss surgery can help people who regained weight after an initial sleeve gastrectomy. The goal is to see if the medicine improves weight-loss outcomes compared to surgery alone.
This study tests a weekly injection of semaglutide (a medication that helps control appetite) in people who have regained weight after weight-loss surgery. The goal is to see if it can help them lose weight again and keep it off.
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