Weekly semaglutide for weight regain after weight-loss surgery
Part of Hormones & metabolism clinical trials.
This study tests a weekly injection of semaglutide (a medication that helps control appetite) in people who have regained weight after weight-loss surgery. The goal is to see if it can help them lose weight again and keep it off.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had weight-loss surgery (sleeve gastrectomy, gastric bypass, or one-anastomosis bypass) at least 18 months ago.
- You lost at least 20% of your body weight after surgery.
- You have regained more than 25% of the weight you lost, confirmed by two weigh-ins at least 2 weeks apart.
- Your current BMI is 30 or higher, or 27 or higher with at least one weight-related health issue (like type 2 diabetes, high blood pressure, or sleep apnea).
- You are able to inject the medication yourself once a week and attend study visits.
- You have not used any weight-loss medication or GLP-1 drugs (like Ozempic or Wegovy) in the past 6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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