Lymphatic surgery for Alzheimer's: a clinical study
Part of Brain & nervous system clinical trials.
This trial tests a surgery that targets the lymphatic system in the neck to help people with moderate-to-severe Alzheimer's disease. The goal is to see if it can improve cognitive function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 50 and 80 years old.
- You have a diagnosis of moderate-to-severe Alzheimer's disease confirmed by a doctor.
- Your dementia rating score is at least 2, and your mini-mental state exam score is below 20.
- You have been on the same medications for at least 1 month and don't plan to change them for 3 months.
- You and your family agree to join the study and sign a consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial is studying a surgery called deep cervical lymphatic venous anastomosis (DC-LVA) for people with Alzheimer's disease. The surgery aims to improve lymphatic drainage in the neck, which may help clear harmful proteins from the brain. Researchers want to see if this surgery can slow memory loss or improve brain function.
This study tests a surgery called lymphaticovenous anastomosis (LVA) as a possible treatment for Alzheimer's disease. The surgery connects tiny lymph vessels to veins to help clear waste from the brain.
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This study tests a surgical procedure to connect lymph vessels in the neck to veins, which may help clear waste from the brain in people with mild cognitive impairment or mild to moderate Alzheimer's disease. It is for patients who have not improved after at least 3 months of standard care.
This study tests a surgery that connects tiny lymph vessels in the neck to improve brain drainage in people with moderate Alzheimer's. It aims to see if this can slow down memory loss.
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