Lymphatic surgery for Alzheimer's disease
Part of Brain & nervous system clinical trials.
This trial tests a surgery that connects tiny lymph vessels to veins in the neck area to help drain waste from the brain. It aims to see if this surgery can improve symptoms of Alzheimer's disease and understand how it works.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a formal diagnosis of Alzheimer's dementia from two senior doctors.
- You need to be between 18 and 80 years old.
- You've had memory or thinking problems for at least one year.
- Your thinking tests must show moderate to severe decline (MMSE score of 24 or lower).
- A brain MRI must show shrinkage in the memory area (hippocampus).
- You must be able to have an MRI and answer test questions, and not be pregnant or have serious other illnesses.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests a surgery called lymphaticovenous anastomosis (LVA) as a possible treatment for Alzheimer's disease. The surgery connects tiny lymph vessels to veins to help clear waste from the brain.
This trial tests a surgical procedure that connects lymphatic vessels in the neck to help clear waste from the brain in people with moderate-to-severe Alzheimer's disease. The goal is to see if this can improve thinking and memory.
This trial tests a surgery called lymphaticovenular anastomosis (LVA) that aims to improve brain drainage in people with Alzheimer's disease. It may help by clearing waste proteins from the brain, potentially slowing the disease.
This study tests a surgical procedure to connect lymph vessels in the neck to veins, which may help clear waste from the brain in people with mild cognitive impairment or mild to moderate Alzheimer's disease. It is for patients who have not improved after at least 3 months of standard care.
This trial tests a surgery that targets the lymphatic system in the neck to help people with moderate-to-severe Alzheimer's disease. The goal is to see if it can improve cognitive function.
This trial tests a surgery that connects lymph vessels in the neck to help clear waste from the brain, which may slow down memory loss in people with moderate Alzheimer's disease. It is for patients who have not improved with standard medications.
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