Neck lymph vessel surgery for severe Alzheimer's disease
Part of Brain & nervous system, Mental health clinical trials.
This study tests a surgery to reconnect tiny lymph vessels in the neck to help drain waste from the brain, which may slow or improve severe Alzheimer's symptoms. It is for people with advanced Alzheimer's who have not gotten better with standard treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- A confirmed diagnosis of Alzheimer's disease (using standard tests and a brain scan or spinal fluid test)
- Aged between 50 and 80 years
- Severe memory and thinking problems (scoring less than 10 on the MMSE test) that have been getting worse for at least 6 months
- No improvement despite taking Alzheimer's medications for more than 6 months
- A caregiver who can help with study visits and spend at least 10 hours a week with the patient
- No other serious brain conditions, recent head injury, or medical problems that would make surgery unsafe
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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