Lymphatic surgery for Alzheimer's disease
Part of Brain & nervous system, Mental health clinical trials.
This study tests a surgical procedure to connect lymph vessels in the neck to veins, which may help clear waste from the brain in people with mild cognitive impairment or mild to moderate Alzheimer's disease. It is for patients who have not improved after at least 3 months of standard care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 50 and 80 years old.
- You have been diagnosed with mild cognitive impairment or mild to moderate Alzheimer's dementia for at least 6 months, and have not gotten better with at least 3 months of standard treatment.
- Your memory and thinking test score (MMSE) is between 12 and 26.
- You have had a positive PET scan or spinal fluid test showing Alzheimer's-related changes in the brain.
- You have a caregiver who spends at least 3 hours with you each day and can help with the study.
- You are not currently taking the Alzheimer's drugs Lecanemab or Donanemab.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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