How age, sex, and exercise affect the heart when blood flow drops
Part of Brain & nervous system clinical trials.
This study looks at how your heart and blood vessels work together when blood flow to your legs is reduced using a special chamber. It compares younger and older adults, and men and women, especially after light exercise.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are either 18 to 35 years old or 65 years or older
- You are generally healthy and don't often feel dizzy, sick, or weak when standing up
- Your blood pressure is below 140/90 when sitting
- Your body mass index (BMI) is under 35
- You exercise no more than 2 days a week in a structured way
- If you are a younger female, you have regular monthly periods
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial looks at how the body's automatic responses (like heart rate and blood pressure) change during and after a type of exercise called blood flow restriction (BFR) training. BFR uses a cuff to reduce blood flow to the muscles, which may make light exercise more effective. This study could help determine if BFR is safe and beneficial for different age groups.
This study looks at how your blood vessels respond to resistance exercise (like weight lifting) with and without a technique called blood flow restriction. It compares younger and older adults to understand how aging affects these responses.
This study tests whether doing low-weight leg exercises with a blood pressure cuff (to partially restrict blood flow) can change how your brain responds to movement. It is for healthy young adults who want to understand how a simple exercise method affects nerve signals.
This trial looks at how blood pressure and heart rate change when standing up or exercising in healthy people and in older adults with high blood pressure. It aims to understand how the body's automatic (autonomic) nervous system controls these functions.
This study tests how different settings of blood flow restriction (using a cuff to partially reduce blood flow) during exercise affect leg strength and function in older adults with age-related muscle weakness. It may help find the best way to improve mobility and independence.
This study tests whether low-intensity exercise with blood flow restriction (using special cuffs on your arms or legs) can improve strength and daily function in older adults. You join online classes from home and go to the campus three times for check-ups.
Hear when a new Orthostatic Intolerance trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.