Comparing two arthritis pills added to methotrexate
Part of Bones, joints & muscles, Immune system & allergy, Skin clinical trials.
This study compares two oral medications, tofacitinib and upadacitinib, when added to methotrexate for people with rheumatoid arthritis. The goal is to see which one works better and is safer for controlling symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with rheumatoid arthritis.
- You have not taken a biologic drug for arthritis in the last 3 months.
- You have no history of serious infections like tuberculosis or sepsis.
- You have no history of cancer in the last 5 years.
- You are not pregnant or breastfeeding, and if you could become pregnant, you use effective birth control.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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