Clin2
NCT06947694Possibly a fitRecruiting

Testing radioimmunotherapy combinations for lung cancer with metastases

NSCLC Stage IV Without EGFR/ALK Mutation

Part of Cancer, Immune system & allergy, Lungs & breathing clinical trials.

This trial explores whether combining radiation therapy with immunotherapy can trigger an immune response that shrinks tumors throughout the body (abscopal effect) in people with non-small cell lung cancer that has spread to 3 to 6 other sites. It tests different patterns of these treatments to see which works best.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
427 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have been diagnosed with non-small cell lung cancer, confirmed by a tissue sample.
  • Your cancer has spread to 3 to 6 other spots in the body (not counting the main tumor).
  • If you have had brain metastases, they are stable and not causing problems.
  • Your tumor does not have certain gene changes (like EGFR, ALK, ROS, BRAF, MET, or RET).
  • You are between 18 and 75 years old and have a good daily function level (ECOG score of 0 or 1).
  • Your doctor expects you to live at least 3 more months, and you are able to have both immunotherapy and radiation therapy.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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