Clin2
NCT06890507Possibly a fitNot yet recruiting

N-acetylcysteine for chest pain with clear arteries

Angina AttacksNon Obstructive Coronary Artery Disease

Treatments studied

Part of Heart & circulation clinical trials.

This trial tests whether N-acetylcysteine (NAC) can reduce chest pain in people who have angina-like symptoms but normal or near-normal heart arteries. It may help women whose chest pain comes from tiny blood vessels not visible on a standard angiogram.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
25 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are a woman aged 18 or older.
  • You have chest pain at least 3 times a week for the last two weeks.
  • Your heart arteries are clear or have only minor blockages (less than 50% narrowing) on an angiogram or CT scan.
  • You are not allergic to N-acetylcysteine.
  • You have not had a heart attack in the last month.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07593157Not yet recruiting
Heart Pain Treatment Study for Women with Normal Arteries

This study helps women with chest pain or heart symptoms who have normal-looking coronary arteries (the blood vessels that feed the heart). Researchers will perform specialized heart tests to understand why you have symptoms, then tailor treatment based on your specific condition.

Montevideo, Montevideo Department
NCT06948201Not yet recruiting
Nitrate supplement for chest pain in women

This trial tests whether taking a simple nitrate supplement (similar to the nitrates in beets) can improve blood flow in the tiny vessels of the heart for women who have chest pain but no blockages in their major arteries. It may help if your heart's small vessels aren't working as well as they should.

Charlottesville, Virginia
NCT00823563Recruiting
Testing heart artery causes of pain without major blockage

This study looks at people who are being checked for possible heart artery–related chest or similar discomfort, but without major artery blockage (non-obstructive arteries). It aims to help doctors understand what might be causing symptoms and guide safer testing.

Stanford, California
NCT00573027Recruiting
Study of heart pain from small artery heart disease

This trial studies people who have chest pain (angina) due to problems with the heart’s small arteries, not a big blockage. It aims to test whether treatment approaches can help these patients by better understanding the cause of their heart-related symptoms.

Los Angeles, California
NCT06311461Recruiting
Acupuncture for stable chest pain

This trial tests whether acupuncture can help relieve symptoms of stable angina, a type of chest pain that happens when your heart isn't getting enough blood. If you have chest pain at least once a week and are already on heart medications, you may be able to join.

Los Angeles, California
NCT06424834Recruiting· Phase 2/Phase 3
Targeted medicines for chest pain without blocked arteries

This study tests if specific heart medicines (like beta-blockers or calcium channel blockers) can help people with chest pain that is not caused by blocked arteries. It aims to treat the tiny blood vessels or spasms that may be the real cause of your pain.

Palo Alto, California

Hear when a new Angina Attacks trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.