Nitrates for moderate-to-high risk pulmonary embolism
Part of Heart & circulation, Lungs & breathing clinical trials.
This trial tests whether a common food additive (nitrates) can help your heart recover faster when you have a serious pulmonary embolism. It is for people with a recent clot and signs of heart strain, but who are not on specific blood thinners or other nitrate medicines.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed pulmonary embolism (blood clot in the lung) with symptoms starting less than 14 days ago.
- Your right heart shows signs of strain (from an imaging test like CT or ultrasound) and a blood test for troponin is above 45.
- You are not currently on strong blood thinners, have a low platelet count, or have a bleeding disorder.
- You are not pregnant, under 18, or unable to give consent.
- You are not taking nitrate medications (like Imdur) or using a prescription mouthwash daily.
- You have a life expectancy of at least 4 months and are not expected to stop active care.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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