Clin2
NCT06948981Likely a fitRecruiting

GT719 Injection for Relapsed CD19+ B-cell Cancers

Hematological Malignancy (Leukemia- Lymphoma)

Treatments studied

Part of Blood & lymphatic, Cancer clinical trials.

This trial tests a new injection called GT719 for adults with B-cell cancers that have come back or not responded to treatment. The cancer cells must have a marker called CD19. The study aims to see if the treatment is safe and works.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
46 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You must volunteer and sign a consent form.
  • You must be able to follow the study plan.
  • Your daily activity level should be good (ECOG score 0 or 1).
  • Your cancer cells must have the CD19 marker, confirmed by lab tests.
  • You cannot have a weak immune system from birth.
  • You must not have had a recent blood clot in your leg or lungs within the last 6 months that needs blood thinners.
  • No other medical conditions that would make it hard to test the treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07131254Recruiting· Early Phase 1
Study of GT719 cell therapy for CD19-positive leukemia or lymphoma

This study is testing a new cell therapy called GT719 for people with B-cell leukemia or lymphoma that has not responded to standard treatments. The therapy targets a protein called CD19 on cancer cells, aiming to kill them.

Ganzhou, Jiangxi
NCT04586478Recruiting· Phase 2
CNCT19 cell therapy for relapsed or resistant non-Hodgkin lymphoma

This Phase 2 trial tests whether an injected cell therapy called CNCT19 can treat non-Hodgkin lymphoma that has come back or did not respond to prior treatment. It may help by targeting specific lymphoma cells, but you must meet several safety and medical eligibility checks.

Beijing, Beijing Municipality
NCT06927466Recruiting· Phase 1
B019 for relapsed or refractory B-cell acute lymphoblastic leukemia

This trial tests a new treatment called B019 for people whose B-cell acute lymphoblastic leukemia has come back or not responded to standard therapy. The treatment targets specific proteins on the cancer cells to help your immune system fight the leukemia.

Beijing
NCT07021209Recruiting· Phase 1
GT719 for returning or hard-to-treat autoimmune neurological diseases

This trial tests a new antibody drug (GT719) for adults with autoimmune neurological diseases that came back or did not get better with standard treatment. It looks at how safe the drug is and how well it works.

Wuhan, Hubei
NCT07122076Recruiting· Early Phase 1
GT719 injection for moderate to severe autoimmune diseases

This trial tests if a new cell therapy called GT719 can help people with moderate to severe lupus, inflammatory myopathy, or systemic sclerosis that hasn't gotten better with standard treatments. It aims to find a new option for those who have not responded well to usual medications.

Shanghai
NCT07205315Recruiting· Early Phase 1
Testing GT801 cell therapy for blood cancer and AIHA

This study tests an investigational cell therapy called GT801 for people whose CD19-positive blood cancer (B-ALL, CLL, or B-NHL) or autoimmune hemolytic anemia (AIHA) has not responded to standard treatments. The therapy is made from your own immune cells, modified to target and destroy cancer cells or abnormal immune cells.

Zhengzhou, Henan

Hear when a new Hematological Malignancy (Leukemia- Lymphoma) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.