Clin2
NCT07021209Possibly a fitRecruiting

GT719 for returning or hard-to-treat autoimmune neurological diseases

Neurological Autoimmune Diseases

Treatments studied

Part of Brain & nervous system, Immune system & allergy clinical trials.

This trial tests a new antibody drug (GT719) for adults with autoimmune neurological diseases that came back or did not get better with standard treatment. It looks at how safe the drug is and how well it works.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
30 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You volunteer to join and follow the study rules (including signing a consent form).
  • Your doctor expects you to live longer than 12 weeks.
  • If you've had other treatments, at least 4 weeks (or 5 half-lives of that drug) must have passed since your last dose.
  • You have not had an organ transplant, spleen removal, or stem cell transplant.
  • You have not had a blood clot in your leg or lung needing blood thinners in the last 6 months.
  • You are not taking 10 mg or more of prednisone (or a similar steroid) daily, or have not taken that dose in the last 7 days (except inhaled steroids).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07275736Recruiting· Early Phase 1
CAR-T cell therapy for autoimmune diseases

This trial tests a treatment called CNCT19, a type of CAR-T cell therapy, for people with certain autoimmune diseases like neuromyelitis optica, myasthenia gravis, or multiple sclerosis that have come back or not responded to other treatments. It aims to see if targeting a specific immune cell (CD19) can help control the disease.

Beijing
NCT07265206Not yet recruiting· Early Phase 1
A new cell treatment for hard-to-treat autoimmune nerve diseases

This trial tests a new cell-based treatment (called HY001N) for people with certain autoimmune neurological diseases that have not responded to standard treatments. The treatment aims to reset the immune system to reduce attacks and improve symptoms.

NCT07748637Not yet recruiting· Early Phase 1
GT802 injection for relapsing or refractory multiple sclerosis

This trial tests an injection called GT802 for people with relapsing or refractory multiple sclerosis (MS) that hasn't responded to other treatments. The goal is to see if the injection is safe and can help control MS symptoms.

Wuhan, Hubei
NCT04561557Recruiting· Early Phase 1
Cell therapy for relapsing nervous system autoimmune diseases

This early-phase trial tests CT103A “CAR-T” cell therapy to treat certain relapsing or treatment-resistant autoimmune diseases that affect the nervous system. It aims to see whether the cells are safe and may help reduce disease activity when standard treatments haven’t controlled symptoms.

Wuhan, Hubei
NCT07132112Recruiting· Early Phase 1
GT719 injection for moderate to severe autoimmune disease

This trial tests an experimental cell therapy (GT719) for people with autoimmune diseases like lupus, inflammatory myositis, or systemic sclerosis that have not responded well to other treatments. It aims to see if this therapy can help control the disease.

Nantong, Jiangsu
NCT07122076Recruiting· Early Phase 1
GT719 injection for moderate to severe autoimmune diseases

This trial tests if a new cell therapy called GT719 can help people with moderate to severe lupus, inflammatory myopathy, or systemic sclerosis that hasn't gotten better with standard treatments. It aims to find a new option for those who have not responded well to usual medications.

Shanghai

Hear when a new Neurological Autoimmune Diseases trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.