Clin2
NCT06950385Possibly a fitRecruiting

Testing eRapa medicine for FAP

Familial Adenomatous Polyposis (FAP)

Part of Cancer, Digestive system, Genetic & congenital clinical trials.

This trial tests a new medicine called eRapa for people with Familial Adenomatous Polyposis (FAP), a condition that causes many polyps in the colon and raises the risk of cancer. The goal is to see if eRapa can help reduce polyps and improve outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
168 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are at least 18 years old.
  • You have been diagnosed with Familial Adenomatous Polyposis (FAP) and have a genetic test confirming it.
  • You have a high-risk feature like many polyps in your colon, rectum, or pouch, or an advanced stage of polyps in the small intestine.
  • You are willing to use birth control (or not donate sperm/eggs) during and for 12 weeks after treatment.
  • You agree to have an endoscopy (a scope test) as part of the study.
  • You do not have any cancer or pre-cancer that was not fully removed, active infections, or a weak immune system.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07689942AVAILABLE
Low-dose rapamycin for familial adenomatous polyposis

This trial provides early access to an experimental drug called eRapa (a low dose of rapamycin) for people with familial adenomatous polyposis (FAP). The drug may help slow or reduce polyp growth, possibly delaying or avoiding surgery.

NCT07729371Not yet recruiting· Phase 1
Study of ST316 for familial adenomatous polyposis

This study tests a new drug called ST316 to see if it can help people with familial adenomatous polyposis (FAP), a condition that causes many polyps in the colon. The goal is to reduce the number or size of these polyps to lower the risk of cancer.

NCT06649825Enrolling by invitation
Vitamin B1 for familial adenomatous polyposis

This trial tests whether taking vitamin B1 can help people with familial adenomatous polyposis (FAP) reduce the number of polyps in their colon or rectum. It is designed for people who still have most of their bowel and have more than 10 polyps.

Shanghai, Shanghai Municipality
NCT07213791Recruiting· Phase 1
Study of a new drug for FAP-positive cancers

This trial tests a new drug (LY4337713) for cancers that have a specific protein called FAP on their surface. It may be an option for people whose cancer has continued to grow after standard treatments.

Newport Beach, California
NCT05552755Recruiting· Phase 1/Phase 2
Drug trial for FAP to reduce pre-cancer growth

This early-phase trial studies REC-4881 in adults with familial adenomatous polyposis (FAP), a condition that causes many colon/rectum and duodenal polyps. It aims to see whether the treatment can safely help control or shrink polyp growth in people who have had bowel surgery.

Scottsdale, Arizona
NCT06308445Not yet recruiting· Phase 2
Rapamycin for teenagers with familial adenomatous polyposis

This trial tests if a drug called rapamycin can help reduce polyps in teenagers with a condition that causes many polyps in the colon. It aims to see if the drug is safe and might help prevent the need for surgery.

Bordeaux

Hear when a new Familial Adenomatous Polyposis (FAP) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.