Expanded access to eRapa for FAP polyps
Part of Cancer, Digestive system, Genetic & congenital clinical trials.
This trial offers access to an experimental drug called eRapa (a form of rapamycin) for people with Familial Adenomatous Polyposis (FAP) who have many polyps in the colon or duodenum. The drug may help reduce polyp growth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are done growing and have reached your full adult height.
- You have Familial Adenomatous Polyposis (FAP) confirmed by a genetic test or a parent with FAP.
- You have a significant number of polyps in your colon, rectum, or duodenum.
- You do not have active cancer or high-grade dysplasia in your digestive tract.
- You do not have a serious ongoing infection, liver or kidney problems, or a history of pancreatitis.
- You are willing to use effective birth control during treatment and for 12 weeks after, and not breastfeed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new medicine called eRapa for people with Familial Adenomatous Polyposis (FAP), a condition that causes many polyps in the colon and raises the risk of cancer. The goal is to see if eRapa can help reduce polyps and improve outcomes.
This study tests a new drug called ST316 for people with Familial Adenomatous Polyposis (FAP) who have already had their colon removed. It aims to see if the drug can help control polyps in the remaining rectum or pouch.
This trial tests the drug rapamycin to see if it can help prevent polyps from growing in children aged 12 to 17 with familial adenomatous polyposis (FAP). The goal is to find out if it can reduce the number or size of polyps, which may lower the risk of needing surgery.
This early-phase trial studies REC-4881 in adults with familial adenomatous polyposis (FAP), a condition that causes many colon/rectum and duodenal polyps. It aims to see whether the treatment can safely help control or shrink polyp growth in people who have had bowel surgery.
This trial looks at how many colon polyps progress toward cancer in people with familial adenomatous polyposis (FAP). It may help doctors better predict risk and guide safer monitoring or treatment for you.
This study reviews duodenal polyps in people with FAP to improve how they are classified. It uses existing medical records from endoscopies (scope tests) to help doctors better understand and manage polyp growth.
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