Ciprofol for blood pressure stability in older adults on heart medications
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether ciprofol, a newer sedative, can help prevent low blood pressure during surgery in older patients who are already taking medications for high blood pressure or heart failure (called RAS inhibitors). It may be a good option if you're 65 or older, on these medications for more than 3 months, and having abdominal surgery lasting over 2 hours.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Having elective abdominal surgery expected to last more than 2 hours
- Age 65 or older
- Taking RAS inhibitor medication (like lisinopril, losartan, or similar) for at least 3 months before surgery
- Classified as ASA II or III (moderate to severe but not incapacitating health condition)
- Able to give informed consent (or have a guardian who can)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a sedative called ciprofol in older adults having a painless colonoscopy. It will measure how the drug affects your heart's ability to pump blood. This may help doctors choose safer sedation for elderly patients.
This study looks at whether the time of day you have surgery affects how well a sedative called ciprofol works and how quickly you recover. It may help doctors choose the best timing for anesthesia.
This trial tests a combination of two sedatives (anricofen and ciprofol) for deep sedation in older adults having an ERCP procedure. It aims to see if this combination is safe and effective for patients between 60 and 90 years old with mild to moderate health conditions.
This study tests a new sedative medicine (ciprofol) to find the best dose for placing a breathing tube mask in children during surgery. It may help your child get a safer, more comfortable experience.
This study compares two sedative medications, ciprofol and propofol, for children (ages 3–11) during tonsil or adenoid removal surgery. It uses special brain-wave monitors (IoC1 and IoC2) to see which drug provides safer, more stable sedation.
This trial studies how the drug ciprofol works in older adults undergoing elective orthopedic limb surgery. The goal is to understand how the body processes the drug and how it affects patients, which may help improve its use for anesthesia in the elderly.
Hear when a new Intraoperative Hypotension trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.