Clin2
NCT06969287Possibly a fitRecruiting

Testing fluvoxamine to prevent confusion after surgery

DeliriumSurgery-Complications

Treatments studied

Part of Brain & nervous system, Mental health clinical trials.

This trial tests if a medication called fluvoxamine can help prevent delirium (sudden confusion and disorientation) after non-cardiac surgery. If you are having surgery that requires at least a 2-day hospital stay, this study may be for you.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
46 people
Ages
60 years and older
Study type
Interventional

Who can take part

  • You must speak English.
  • You are scheduled for surgery that is not on the heart or brain and will stay in the hospital for at least 2 days.
  • You have not taken any experimental drugs in the last 7 weeks.
  • You do not have a known allergy or sensitivity to fluvoxamine or similar antidepressants (SSRIs).
  • You are not planning to need a breathing tube after surgery.
  • You do not have a history of drug or alcohol dependence, or take certain medications that could interact with fluvoxamine.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06192615Recruiting· Phase 3
Can a sleep medication protect the brain after heart surgery?

This study tests whether a medicine called dexmedetomidine, given after heart surgery, can help prevent confusion and thinking problems in older adults during their intensive care stay. If you are 60 or older and having heart surgery with a heart-lung machine, this trial might be for you.

Los Angeles, California
NCT05949229Not yet recruiting· Phase 1/Phase 2
Duloxetine before cancer surgery to prevent confusion afterward

This trial tests whether taking the medicine duloxetine before cancer surgery can help prevent confusion (delirium) after surgery. If you are having cancer surgery and do not already have memory or thinking issues, this study might help you recover more clearly.

Asyut
NCT06248684Not yet recruiting
Preventing confusion after surgery in older adults

This study tests ways to prevent confusion (delirium) after surgery in older adults. It aims to help you stay clear-headed and recover better after your operation.

NCT07217912Recruiting· Phase 2
Study of daridorexant to prevent confusion after heart surgery

This trial tests whether a sleep medication called daridorexant can help prevent delirium (sudden confusion) in older adults after heart surgery. You must be 60 or older and having a specific type of heart operation.

Rochester, New York
NCT04707794Recruiting
Preventing confusion after non-heart surgery in older adults

This study looks at how often older adults develop sudden confusion (delirium) after non-heart operations under general anesthesia. It may help doctors better predict who is at risk and improve care after surgery.

New Delhi, National Capital Territory of Delhi
NCT05990790Recruiting· Phase 4
Comparing anesthetics and their effect on confusion after surgery

This study compares three different anesthesia medicines to see which one might lower the chance of confusion or delirium after major surgery. If you are 65 or older and having a long, planned non-heart surgery, this trial could help determine the safest option for you.

Innsbruck

Hear when a new Delirium trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.