Clinical trials
Delirium clinical trials
Below are recruiting delirium clinical trials, each written for real people, not researchers. We’re tracking 205 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05915377Recruiting
Screening for hospital confusion in older adults
This trial is testing practical ways to recognize delirium, a sudden type of hospital confusion, in older patients. It may help your care team spot confusion earlier and respond sooner.
Boston, MassachusettsAges 70 years+ - NCT07202208Recruiting
Preventing confusion after hip fracture surgery
This trial tests a special care plan (the 'Delirium Zero Protocol') to help prevent confusion (delirium) after hip fracture surgery. It is for people over 65 who are having hip fracture surgery and have a family member or caregiver who can be involved.
Manises, ValenciaAges 65 years+ - NCT07396532Recruiting
iPad messages to prevent delirium after hip fracture surgery
This trial tests if audio-recorded messages played on an iPad can help prevent confusion (delirium) after hip fracture surgery in older adults. It is for people aged 60 and older who do not have a history of memory or thinking problems.
SingaporeAges 60 years+ - NCT07759310Recruiting
Teamwork training for ICU nurses to reduce delirium
This study is testing a training program that helps ICU nurses improve how they prevent and manage delirium (a state of confusion that can happen in hospital). If you are an ICU nurse, this training could help you feel more confident in caring for patients with this condition.
Pisa, PIAges 18 years+ - NCT07719712Recruiting
Thinking and confusion after prostate surgery in older adults
This study looks at how older adults' thinking and memory may change after a common prostate surgery, and whether some patients become confused or delirious afterward. It may help doctors understand who is at risk for these problems.
MuğlaAges 65 years+ - NCT07449416Recruiting
Ceribell Delirium Monitor Study in ICU Patients
This pilot study tests a special brain monitor (called Ceribell EEG) to see if it can help detect delirium in ICU patients. Delirium is a state of confusion that can happen during a serious illness, and this monitor may help doctors catch it early.
Irvine, CaliforniaAges 18 years+ - NCT04824144RecruitingPhase 1/Phase 2
Dexmedetomidine for agitation in palliative care delirium
This trial tests whether dexmedetomidine can help calm agitation caused by delirium in adults receiving palliative (comfort-focused) care. It may help reduce restlessness and distress when standard approaches may not be enough.
Calgary, AlbertaAges 18 years+ - NCT05242419Recruiting
Huperzine A to reduce confusion after non-heart surgery
This trial studies whether a medicine called huperzine A can reduce “postoperative delirium,” which is sudden confusion after surgery, in older adults. It focuses on people having non-heart surgery under general anesthesia for at least two hours.
Wenzhou, ZhejiangAges 75 years+ - NCT05461092RecruitingEarly Phase 1
Nerve blocks to improve pain control after spinal fusion
This early-stage study tests whether a regional nerve block can improve pain control and recovery for older adults having elective lumbar spinal fusion. If you qualify, you may receive a special pain-control injection during surgery to reduce opioid needs and improve recovery comfort.
Iowa City, IowaAges 65 years+ - NCT05950958Recruiting
Preventing ICU confusion with several supportive care steps
This trial tests whether a set of different care steps in the ICU can help prevent delirium, a sudden episode of confusion. It may help people who are at higher risk because they will likely need ICU care for more than a day.
SeoulAges 50 years+ - NCT06172491Recruiting
Automated tool to measure ICU delirium severity
This study tests a computerized tool that automatically measures how severe delirium (sudden confusion) is for ICU patients. Researchers want to see if it can help monitor and manage delirium better without adding extra work for nurses.
Rochester, MinnesotaAges 50 years+ - NCT06268080Recruiting
Sedation depth and mental recovery after surgery for older adults
This trial tests whether monitoring how deeply you sleep during anesthesia helps prevent confusion and memory problems after surgery. It is for older adults who can give consent and are having a major operation.
Grafton, AucklandAges 55 years+ - NCT06510140Recruiting
Brain monitoring and frailty to predict confusion after surgery in older adults
This study tests if monitoring your brain waves during surgery and checking your frailty level can help predict whether you might become confused after surgery. It aims to improve care for older adults having major non-cardiac operations.
Saint-EtienneAges 75 years+ - NCT06650436Recruiting
Stroke, Delirium, and Long-Term Thinking Changes
This study looks at the link between stroke, delirium (sudden confusion), and long-term thinking problems. It tests whether EEG and MRI scans can help predict who may have trouble thinking clearly after a first stroke.
BrusselsAges 18 years+ - NCT06721819RecruitingPhase 3
Sleep and brain training before heart surgery to prevent delirium
This study tests whether a combination of sleep therapy, brain games, and light exercise before heart surgery can help prevent confusion or disorientation (delirium) after the operation. Participants will be asked to use a tablet and fitness tracker daily for about an hour before their surgery.
Boston, MassachusettsAges 60 years+ - NCT06817239Recruiting
Low-dose esketamine for preventing confusion after surgery in older adults
This study tests whether a low dose of the medicine esketamine can help prevent confusion after surgery in older adults at higher risk. You may qualify if you are 65 or older, planning a major non-cardiac surgery, and have certain health conditions like high blood pressure or diabetes.
Fuzhou, FujianAges 65–90 - NCT06818409Recruiting
Blood test to predict confusion after hip fracture surgery
This study looks at a simple blood test called CALLY (CRP-Albumin-Lymphocyte) to see if it can predict which older adults might become confused after hip fracture surgery. The goal is to identify those at risk early so doctors can take steps to prevent or manage delirium.
Ankara, KeçiörenAges 65 years+ - NCT07193797Recruiting
A study on confusion after ICU discharge
This study looks at different kinds of confusion (delirium) that can happen after a serious illness and how that may affect you as you heal outside the ICU. The goal is to understand these patterns better to help future patients.
Shanghai, Shanghai MunicipalityAges 18–100 - NCT07258082Recruiting
Ear stimulation for delirium in hospital patients
This study tests a gentle electrical stimulation device placed on the ear to see if it can help reduce confusion (delirium) in hospitalized patients. It is for adults who are right-handed and currently experiencing delirium.
Stony Brook, New YorkAges 22 years+ - NCT07435675Recruiting
Nerve block to prevent agitation after ear surgery in children
This study tests if a nerve block behind the ear can help children ages 5–14 stay calm and comfortable after middle ear surgery. It may reduce confusion and restlessness when waking up from anesthesia.
Al Fayyum, Faiyum GovernorateAges 5–14 - NCT07641153Recruiting
Virtual Reality Games to Prevent Confusion After Surgery
This study tests whether playing cognitive games in virtual reality (VR—a computer-generated environment you interact with using a headset) can help prevent delirium (severe confusion) in older adults after major surgery. Delirium is common after surgery in seniors and can slow recovery; this trial explores whether VR brain exercises might reduce it.
Houston, TexasAges Up to 65 years - NCT05541276RecruitingPhase 3
Melatonin to prevent waking confusion in young children after surgery
This study tests whether giving melatonin before surgery can help prevent agitation and confusion in young children after they wake up from anesthesia. Participation may help your child have a smoother recovery after their procedure.
Copenhagen, Capital RegionAges 1–6 - NCT07726875Enrolling by invitation
Orexin and confusion after surgery in older adults
This study looks at a brain chemical called orexin (which helps control wakefulness) in older adults after surgery. The goal is to see if orexin levels are linked to confusion or agitation that can happen when waking up from anesthesia. If you take part, your blood will be tested before and after surgery.
Shanghai, Shanghai MunicipalityAges 60 years+ - NCT06680336Recruiting
Cognitive Recovery After Stroke-Related Confusion
This study tests whether a special program can help your thinking and memory recover after a stroke that caused confusion (delirium). You may be able to join if you had a recent ischemic stroke, are 60 or older, and do not have dementia or a severe language problem.
TübingenAges 60 years+
Hear when a new Delirium trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Delirium trials by city
Studies with a site in or near these metro areas.
Delirium trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for delirium?
- Yes. Clin2 currently lists 205 recruiting delirium studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a delirium trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a delirium trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.