Study of a new drug for advanced solid tumors with MSI-H or dMMR
Treatments studied
Part of Cancer, Digestive system, Women’s health & pregnancy clinical trials.
This trial tests an oral medication called MOMA-341 in people with advanced solid tumors that have high microsatellite instability (MSI-H) or mismatch repair deficiency (dMMR). It aims to see if the drug can help when prior immunotherapy hasn't worked or isn't available.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You have an advanced or metastatic solid tumor that is MSI-H or dMMR and has not responded to prior immunotherapy (or you were unable to get it).
- You have at least one tumor that can be seen on scans.
- You are able to perform daily activities with few or no limitations (ECOG performance status 0-2).
- You have recovered from side effects of previous treatments, and your organs are working well enough.
- You agree to use effective contraception if applicable.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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