Studying MOMA-313 for advanced or metastatic solid tumors
Treatments studied
Part of Cancer, Digestive system, Hormones & metabolism, Kidney & urinary, Skin, Women’s health & pregnancy clinical trials.
This trial tests a new oral drug, MOMA-313, alone or with another drug (olaparib), in people whose cancer has a specific DNA repair problem (HR-deficient mutation). It aims to see if the drug can shrink tumors or slow their growth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- Your cancer must have a specific genetic change called an HR-deficient mutation.
- You must have at least one tumor that can be seen on scans (measurable or not).
- You must be able to do daily activities with little help (ECOG score 0-2).
- You must have recovered from side effects of prior treatments (hormone therapy and palliative radiation are okay).
- You cannot have had prior treatment with a polymerase theta inhibitor.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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