Avoiding brain radiation when chemo or other drugs work
Part of Brain & nervous system, Cancer clinical trials.
This trial tests whether some people with brain metastases from solid tumors can safely skip radiation if their cancer drugs (like targeted therapy, immunotherapy, or certain chemotherapies) shrink the brain tumors. You will get MRI scans to see if the drugs are working.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a solid tumor cancer that first appeared within the last 5 years or has clear evidence of spread beyond the brain.
- You plan to start or have just started a type of cancer treatment that is expected to shrink brain tumors (e.g., targeted pills, immunotherapy, some chemotherapies, or certain hormone therapies).
- You have at least one brain metastasis that is not being treated with radiation or surgery, and all such tumors are no larger than 3 cm.
- You must be able to have MRI scans of the brain with contrast (dye) and the scan slices are very thin (1.5 mm or less).
- You are 18 or older, awake and self-caring most of the day (Karnofsky score >60), and willing to sign consent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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