Combination treatment for HER2-positive breast cancer that has spread to the brain
Part of Cancer, Skin clinical trials.
This trial tests two new drugs, SHR-A1811 and THPy, for women with HER2-positive advanced breast cancer that has spread to the brain. It aims to see if this combination can shrink brain tumors and improve outcomes for patients who have not yet had systemic treatment for advanced disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman aged 18 or older.
- You have HER2-positive advanced breast cancer confirmed by biopsy.
- You have newly diagnosed brain metastases, with at least one tumor that can be measured on an MRI.
- You have not received any systemic treatment (like chemotherapy or hormone therapy) for advanced breast cancer.
- You have adequate organ function and are willing to participate and follow the study plan.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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