Knee replacement study looks at bone-brain pain link
Part of Bones, joints & muscles, Brain & nervous system, Pain clinical trials.
This study looks at how signals from the bone near the knee might affect the brain's pain centers. It aims to understand the connection to help improve treatments for severe knee osteoarthritis in people having knee replacement surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have knee osteoarthritis that has been confirmed by a doctor.
- You are between 60 and 70 years old.
- Your knee X-ray shows very severe osteoarthritis, often called 'grade IV'.
- You are scheduled to have total knee replacement surgery.
- You have not taken steroids or bone-strengthening drugs in the last 6 months.
- You are able to have an MRI scan (no metal implants or other reasons you can't).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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