Personalized pain relief for knee osteoarthritis
Treatments studied
Part of Bones, joints & muscles, Pain clinical trials.
This study tests a personalized approach to managing knee osteoarthritis pain by engaging the brain's natural pain-control systems. It aims to find the best way to reduce pain for each person, potentially offering a new option for those with long-term knee pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had knee pain for more than 6 months.
- Your knee pain is moderate to severe (more than 3 out of 10) on most days in the past month, due to osteoarthritis.
- You are between 45 and 80 years old.
- You have X-ray evidence of significant knee joint changes (Kellgren-Lawrence grade 2-4).
- You are able to speak and read English.
- You are not currently taking certain antidepressants or tramadol, and you have not used duloxetine in the last 3 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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