Brain imaging study of dopamine in early psychosis risk
Treatments studied
Part of Mental health clinical trials.
This study uses brain scans and a medication called methylphenidate (Ritalin) to understand how the brain chemical dopamine works in people at early risk for psychosis. It may help researchers find better ways to predict and treat psychosis.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 30 years old.
- You have been identified as at Clinical High Risk for psychosis.
- You have NOT taken antipsychotic medication in the past 3 weeks, or you have never taken it.
- You do not have a current substance abuse problem (other than nicotine or caffeine) in the last month.
- You are not a daily smoker.
- You are not pregnant, breastfeeding, or have an unstable medical condition.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new drug called MT1988 in people who show early warning signs of psychosis. Researchers want to see if it changes certain markers in the body related to mental health.
This trial tests if cannabidiol (a non-psychoactive cannabis component) can prevent psychosis in people ages 12-35 at high risk. It compares CBD to a placebo to see if it reduces symptoms and delays or prevents a first psychotic episode.
This research study looks at how the brain changes in young people who are at high risk for developing psychosis. It aims to find better ways to predict and prevent psychosis by using brain imaging and thinking tests.
This study uses brain scans (PET and MRI) to see how a specific receptor, called D3, is affected by antipsychotic medications in people with schizophrenia. You may be able to participate if you have not taken antipsychotics for at least 3 weeks and are not using nicotine products.
This study uses brain scans to find markers that can predict how well antipsychotic medications work in people having their first episode of psychosis. It aims to help doctors choose the right treatment earlier.
This early-phase study uses a PET brain scan (a special imaging test) to see how the brain responds in people with cocaine use disorder. It aims to better understand brain activity and whether this scan approach could help research or future treatments.
Hear when a new Clinical High Risk for Psychosis (CHR) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.