Clin2
NCT04038840Possibly a fitRecruiting

Brain PET-MR imaging to study schizophrenia connections

Schizophrenia

Part of Mental health clinical trials.

This early (Phase 1) study uses a special brain scan to look at synapses—the contact points between brain cells—in people with schizophrenia-related conditions. It helps researchers understand brain activity and connection patterns, which may guide future tests or treatments.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
60 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You are age 18 to 65
  • If you have schizophrenia-related illness: your meds have been stable for at least 2 weeks
  • You must be able to do the PET-MR scan without sedation (sleep medicines)
  • You cannot have had substance use in the last 3 months
  • You must be able to safely have an MRI scan (no incompatible metal/implants and you can fit in the scanner)
  • You must not be pregnant or breastfeeding

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04807530Recruiting
MRI brain study for people with schizophrenia symptoms

This study uses brain scans to look at how a specific brain area works in schizophrenia. If you qualify, it may help researchers better understand the brain changes linked to symptoms.

San Francisco, California
NCT07715253Not yet recruiting· Phase 1
Brain imaging study of antipsychotics in schizophrenia

This study uses brain scans (PET and MRI) to see how a specific receptor, called D3, is affected by antipsychotic medications in people with schizophrenia. You may be able to participate if you have not taken antipsychotics for at least 3 weeks and are not using nicotine products.

NCT03649581Recruiting
Brain-scan study in catatonia and hebephrenia with stable schizophrenia

This study measures brain signals during scans to look for patterns linked to two types (subforms) of psychotic disorders. If you have schizophrenia or schizoaffective disorder and your symptoms have been stable, you may be able to help researchers understand these brain markers.

Strasbourg
NCT01730781Recruiting
PET scan study to image cannabinoid receptors in the brain

This study uses a special brain scan (PET) to measure cannabinoid receptors—areas in the brain that interact with cannabis-like chemicals. It may help researchers better understand how these receptors relate to conditions such as schizophrenia, PTSD, opioid use disorder, or early psychosis risk.

New Haven, Connecticut
NCT07108673Not yet recruiting
Brain structure study for people with schizophrenia

This study uses a special MRI technique to measure brain structure differences in people with schizophrenia, including those who also have nicotine dependence. Your participation could help researchers understand more about the condition.

NCT06236048Recruiting
Brain energy and glutamate in schizophrenia

This study uses brain scans (MRI and PET) to look at energy use and a brain chemical called glutamate in people with schizophrenia. It compares healthy volunteers to those with well-controlled schizophrenia and those with hard-to-treat schizophrenia to understand the biology better.

London

Hear when a new Schizophrenia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.