Early norepinephrine for trauma patients with heavy bleeding
Treatments studied
Part of Injuries & trauma clinical trials.
This trial tests whether giving norepinephrine early helps adults with severe bleeding from injury. It is for patients who have lost a lot of blood or show signs of shock.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old and had a serious injury.
- You have lost at least half a liter of blood from an external wound or have signs of internal bleeding.
- You have signs of shock, like very low blood pressure, slow blood flow (capillary refill longer than 2 seconds), or high lactate levels.
- You do not have severe brain injury, limb damage with no blood flow, or certain medical conditions like heart or kidney disease.
- You are not pregnant and have not already received similar blood-pressure-raising medicines.
- You are not allergic to norepinephrine or taking certain medicines like ergotamine or MAO inhibitors.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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