Calcium and vasopressin for bleeding shock after major injury
Treatments studied
Part of Hormones & metabolism, Injuries & trauma, Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial tests whether giving calcium and vasopressin early can improve outcomes in people with major injury who are at risk for life-threatening bleeding shock. It mainly includes patients who need rapid blood transfusion and likely major surgery to stop bleeding.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had a serious injury and emergency team thinks you are at risk from dangerous bleeding
- Your systolic blood pressure is very low (≤ 90) with fast heart rate (≥ 108) OR your systolic blood pressure is extremely low (≤ 70)
- Blood transfusion has started in the field or within 60 minutes of arriving at the trauma center
- The care team plans major surgery to control bleeding within 60 minutes of arriving (like opening the chest/abdomen or repairing major blood vessels)
- You are expected to be admitted to the ICU
- You can receive study treatment (the team must be able to place an IV or similar access line, and you must not have opted out)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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