Clin2
NCT06994507Possibly a fitRecruiting

GM1 to prevent nerve damage from breast cancer chemo

Chemotherapy-induced Peripheral Neuropathy (CIPN)

Part of Brain & nervous system, Cancer clinical trials.

This trial tests whether a drug called GM1 can prevent nerve damage (numbness, tingling, or pain in hands/feet) caused by a common chemotherapy drug used for breast cancer. If you are starting chemotherapy with nab-paclitaxel, this study may help protect your nerves.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
352 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are a woman aged 18 to 75 with breast cancer.
  • You are scheduled to receive a chemotherapy drug called albumin-bound paclitaxel (also called nab-paclitaxel) as part of your treatment.
  • You do not already have numbness, tingling, or pain in your hands or feet from nerve damage (peripheral neuropathy).
  • You have not had any other cancer besides breast cancer.
  • You can keep track of your symptoms and report them through simple questionnaires.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07377279Recruiting
Acupuncture and compression to prevent nerve pain from chemo

This trial tests whether acupuncture and compression therapy can prevent nerve damage caused by taxane chemotherapy in early-stage breast cancer. It aims to reduce numbness, tingling, or pain in the hands and feet.

Guangzhou, Guangdong
NCT07142304Recruiting
A study of compression gloves and boots to prevent chemo nerve damage

This trial is testing a wearable device (gloves and boots) that applies gentle compression to your hands and feet during chemotherapy. It aims to prevent or reduce nerve damage (numbness, tingling, pain) that some chemotherapy drugs can cause.

Poway, California
NCT04715542Not yet recruiting· Phase 3
Drug to help prevent chemotherapy nerve pain in breast cancer

This Phase 3 trial tests whether Stibium metallicum (a study supplement/medication) can prevent nerve damage in the hands and feet caused by paclitaxel chemotherapy. If you’re about to start a specific paclitaxel schedule for early breast cancer, this may help reduce the risk of painful numbness or tingling.

NCT07423390Recruiting· Phase 3
Vitamin B12 to prevent nerve damage from chemo

This trial tests if taking mecobalamin (a form of vitamin B12) can prevent or reduce nerve pain and numbness caused by taxane chemotherapy. It may help people getting chemo for several types of cancer.

Xining, Qinghai
NCT07082764Not yet recruiting· Phase 2
TAR-0520 gel to prevent nerve damage from taxane chemotherapy

This trial tests whether a gel called TAR-0520 can prevent nerve damage (peripheral neuropathy) caused by common breast cancer drugs like paclitaxel or docetaxel. You'll apply the gel to your skin, and the study will see if it helps reduce numbness, tingling, or pain in your hands and feet.

Marseille
NCT07601386Not yet recruiting· Phase 1
Testing JMKX000189 for Chemo-Related Nerve Pain

This trial tests a new drug called JMKX000189 to see if it can safely reduce nerve pain and tingling caused by cancer chemotherapy. If you've completed cancer treatment and are struggling with these symptoms, this study may help.

Shanghai

Hear when a new Chemotherapy-induced Peripheral Neuropathy (CIPN) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.