Stem cell treatment for kidney transplant rejection
Part of Immune system & allergy, Kidney & urinary clinical trials.
This study tests whether a treatment made from stem cells can help people who have a specific kind of kidney transplant rejection that happens over time. The goal is to see if it can stop the rejection and help keep the kidney working longer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had a kidney transplant.
- You have been diagnosed with chronic active antibody-mediated rejection, a specific type of rejection that can happen months or years after the transplant.
- You are willing to take part in a study that tests a new treatment using stem cells.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This early-phase trial tests a new therapy that uses your own immune cells to reduce your body's attack on a new kidney. It aims to help people who are highly sensitized (hard to match) get a transplant successfully.
This study tries to use a stem cell transplant from your original kidney donor to help your body accept the kidney without needing lifelong anti-rejection drugs. You must have a perfectly matched sibling donor who is still available.
This trial tests if a special stem cell treatment (using your own stem cells) can reset your immune system so you can accept a kidney from a deceased donor, even if you have very high antibody levels that make it hard to find a match. It's for people who have been waiting a long time and haven't had a transplant offer.
This study looks at different treatments for a type of kidney transplant rejection called antibody-mediated rejection, where the body's immune system attacks the new kidney. It aims to understand how these treatments work and how they might help people keep their transplanted kidney healthy.
This trial tests whether giving a special type of umbilical cord cell can help treat a form of kidney rejection that hasn't improved with standard antibody treatment. It aims to slow down or stop further kidney damage.
This Phase 2 study tests a combined treatment—kidney transplant plus stem cell–based immune therapy—to help the body accept the new kidney with less immune attack. You may be able to take part if you have a matching sibling donor and meet key safety and health requirements.
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