Study of a dissolving scaffold for leg artery blockages
Part of Heart & circulation clinical trials.
This trial tests a new type of absorbable scaffold (like a temporary mesh) that is placed inside a blocked artery below the knee to restore blood flow. It is for people with severe leg pain or small ulcers due to chronic limb-threatening ischemia (CLI) who have a short blockage in a specific artery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe leg pain or small ulcers (Rutherford category 4 or 5) due to blocked arteries below the knee.
- The blockage is in a short segment (18 mm or less) of an artery below the knee, and the vessel diameter is between 3.0 and 3.4 mm.
- You are able to take blood thinners (like aspirin and clopidogrel) for at least 3 months after the procedure.
- You have not had a stroke in the past 3 months, your kidney function is reasonably good, and you have no major bleeding or immune system problems.
- There is no metal stent already in the target artery, and the artery has not been treated with balloon angioplasty in the last 60 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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