Testing gecacitinib for chronic graft-versus-host disease after 2 or more treatments
Treatments studied
Part of Immune system & allergy, Lungs & breathing clinical trials.
This trial tests a new drug, gecacitinib, for patients with moderate to severe chronic graft-versus-host disease (cGVHD) that has not improved after 2 to 5 prior treatments. It aims to see if the drug is safe and effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and have signed a consent form.
- You have had a stem cell or bone marrow transplant from any donor.
- Your blood counts (white cells and platelets) are high enough and you haven't needed growth factor shots or blood transfusions in the last week.
- You have been diagnosed with moderate or severe chronic GVHD according to standard guidelines.
- You have already tried 2 to 5 different treatments for your GVHD and it is still active.
- You are able to swallow tablets and your daily activity level is fairly good (ECOG score 0-2).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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