Brain effects of a serotonin blocker in healthy adults
Treatments studied
This study tests how a drug that blocks a serotonin receptor affects thinking, memory, and mood. It helps researchers understand the role of serotonin in the brain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 45 years old.
- You have good vision and hearing.
- Your body mass index (BMI) is between 18 and 35.
- You speak English well enough to understand the tasks.
- You are not currently being treated for any mental health condition and have no history of serious psychiatric disorders.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether taking pimavanserin before psilocybin changes the drug's effects in healthy volunteers who have never used psychedelics. It aims to understand how to make psychedelic therapy safer and more predictable.
This study tests how psilocybin (the active ingredient in magic mushrooms) affects consciousness by blocking a specific serotonin receptor in the brain. It helps researchers understand why psilocybin causes altered states of mind.
This Phase 1/2 study tests psilocybin to see how it affects brain signals and the “content” of thoughts while you are monitored during the study. Because participants must be generally healthy and mentally stable, it may be an option if you meet those safety and medication rules and are comfortable having your brain activity measured.
This study tests how psilocybin, a substance that can cause hallucinations, affects memory and brain activity in healthy adults. It may help us understand how psilocybin could be used for mental health treatments.
This study uses a special PET brain scan tracer to better understand serotonin receptor activity in people with certain neurodegenerative conditions, especially when they develop hallucinations or delusions. The results may help researchers improve how these brain changes are measured and tracked over time.
This Phase 1 study tests how a serotonin-related drug changes brain activity in healthy adults, using brain imaging (MRI) and other measures. Because it involves a drug that may affect the brain, eligibility is designed to keep the results safe and clear.
Hear when a new Healthy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.