Delirium risk in older adults given common antibiotics
Part of Brain & nervous system, Mental health clinical trials.
This study looks at whether certain antibiotics (ceftazidime, cefepime, or ceftriaxone) raise the chance of confusion or delirium in hospitalized adults 65 and older. The goal is to find out which antibiotic might be safest for the brain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 65 years or older.
- You are currently hospitalized with an infection and are being treated with one of these antibiotics: ceftazidime, cefepime, or ceftriaxone.
- You did not have confusion or delirium before this hospital stay.
- You are not allergic to any cephalosporin antibiotics.
- You are not in septic shock (severe infection causing organ failure).
- You are not taking medications that can cause confusion, such as certain sedatives, sleeping pills, or strong painkillers (like opioids).
- You do not have severe liver disease, kidney failure requiring dialysis, or a major electrolyte imbalance.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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