Clin2
NCT07028242Possibly a fitNot yet recruiting

Ultrasound and tissue checks for early uterine cancer treatment

Fertility-Sparing Treatment (FST)Atypical Endometrial HyperplasiaEarly Endometrial Cancer (EEC)

Part of Cancer, Women’s health & pregnancy clinical trials.

This study looks at how ultrasound and tissue samples (histology) can better guide fertility-sparing treatment for early uterine cancer or precancer. It aims to improve how doctors decide on surgery or hormone therapy to preserve fertility.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
50 people
Ages
18 years to 45 years
Study type
Observational

Who can take part

  • You are a woman aged 18 to 45.
  • You have been diagnosed with atypical endometrial hyperplasia (precancerous changes in the uterine lining) or endometrioid endometrial cancer that is low grade (grade 1 or 2).
  • You are a candidate for fertility-sparing treatment, such as hysteroscopic resection (removing abnormal tissue through a scope) or progestin therapy (hormone treatment).
  • You have not had a prior hysterectomy or other non-conservative surgery for this condition.
  • You have no signs that the cancer has spread into the muscle layer of the uterus (no myometrial invasion).
  • You are not pregnant and agree to participate in the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05647109Recruiting
Test tumor-like cell clusters to predict progesterone response

This study looks at small lab samples taken from early endometrial cancer to see how sensitive the tumor is to progesterone treatment. It may help doctors choose the safest treatment that preserves fertility and the uterus for the right patients.

Beijing, Beijing Municipality
NCT03463252Recruiting· Phase 2/Phase 3
Hormone IUD to preserve fertility in early uterine cancer

This study looks at whether a hormone-releasing IUD (LNG-IUS) can treat early-stage endometrial cancer or very early abnormal cell growth while helping you keep the option for future pregnancy. It aims to see how well the treatment works and how it affects fertility-related outcomes.

Chengdu, Sichuan
NCT05051722Recruiting
Test DNA blood and tissue markers to detect gynecologic cancers

This study looks for “methylated DNA markers” (special DNA patterns) to help detect endometrial, ovarian, and cervical cancers, and to support doctors around planned procedures. It may help find cancer earlier or better sort out who needs closer treatment.

Phoenix, Arizona
NCT07077876Recruiting
Endometrial cancer and hyperplasia with conservative treatment

This study looks at women with endometrial adenocarcinoma or atypical hyperplasia who had conservative treatment instead of radical surgery. It aims to check how well the treatment works for both cancer and future pregnancy outcomes.

Roma
NCT04362046Recruiting
Fertility-friendly treatment for early uterine cancer or precancer

This trial studies whether removing an early, hormone-responsive uterine growth using a procedure through the cervix can keep fertility possible. It is for people under 40 with a specific low-risk uterine biopsy and MRI findings who have already tried hormone treatment.

Vancouver, British Columbia
NCT06799624Not yet recruiting
Genetic testing for fertility-sparing endometrial cancer treatment

This study looks at how genetic features of early-stage endometrial cancer affect the success of fertility-sparing treatments. It aims to help women under 45 who want to preserve their fertility understand their treatment options.

Milan, Michigan

Hear when a new Atypical Endometrial Hyperplasia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.