New drug combo for advanced prostate cancer
Treatments studied
Part of Cancer, Kidney & urinary clinical trials.
This study tests whether adding the investigational drug mevrometostat to the standard treatment enzalutamide works better than enzalutamide alone for men with prostate cancer that has spread to other parts of the body (metastatic castration-sensitive prostate cancer). You may benefit if you haven't yet received chemotherapy or similar strong treatments for this stage of cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a man aged 18 or older with prostate cancer that has spread to other parts of the body (bone or other organs).
- You have not yet received chemotherapy or other strong treatments for this stage of your cancer (called metastatic castration-sensitive, or mCSPC).
- You are in good enough health to do your usual daily activities (ECOG score 0 or 1).
- You do not have a serious heart condition, known brain metastases, or active thoughts of self-harm.
- You are not allergic to the study drugs or currently taking medications that strongly affect an important liver enzyme (CYP3A4).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a new medicine (BMS-986365) against the doctor's choice of standard therapy for men with metastatic castration-resistant prostate cancer. It aims to see which treatment works better and is safer.
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