Better surgery for sarcoma using a special dye
Treatments studied
Part of Cancer clinical trials.
This trial tests if taking a drug called 5-ALA before surgery makes sarcoma tumors glow, helping surgeons remove all cancer cells. It's for people with certain types of soft tissue sarcoma that are more aggressive (grades 2 or 3) and are scheduled for surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a soft tissue sarcoma that is grade 2 or 3, meaning it is more likely to grow or spread.
- You are scheduled to have surgery to remove the sarcoma.
- You are 18 years or older.
- You are in generally good health (able to do daily activities without significant help).
- Your blood counts and liver/kidney function are within certain safe ranges.
- You are not pregnant or breastfeeding and will use effective birth control during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether adding immunotherapy drugs (anlotinib and penpulimab) to radiation before surgery can help treat soft tissue sarcoma—a type of cancer in muscles, fat, or connective tissue. The goal is to shrink the tumor and improve surgical outcomes.
This trial tests a precision medicine approach by giving targeted therapy before surgery for high-risk soft tissue sarcoma. The goal is to see if matching treatment to your tumor's type can improve outcomes.
This trial tests a combination of targeted therapy, chemotherapy, and radiation for advanced soft tissue sarcoma that has not responded to standard treatment. It aims to see if the combination can help patients live longer or shrink their tumors.
This trial tests if giving a short course of radiation therapy combined with immunotherapy before surgery can improve outcomes for people with soft tissue sarcoma in the belly or pelvis. It is for patients whose tumors are hard to remove completely without this pre-treatment.
This trial tests a newer way of giving radiation (spatially fractionated) compared to standard radiation for people with large soft tissue sarcomas. It aims to see if the new method works better.
This trial tests a new combination of radiation therapy and an immunotherapy approach (called PraG) for people with advanced soft tissue sarcoma that can't be removed by surgery or has spread. The goal is to see if this treatment can shrink tumors and improve outcomes.
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