Using a light-sensitive agent to improve sarcoma removal
Treatments studied
Part of Cancer clinical trials.
This trial tests whether taking a special medication (5-ALA) before surgery makes the sarcoma glow under a special light, helping the surgeon see and remove the cancer more completely. The goal is to reduce the chance of leaving any cancer behind.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a soft tissue sarcoma that is grade 2 or 3 (moderate or high grade).
- Surgery to remove the sarcoma is already planned as part of your care.
- You are 18 years old or older.
- You are generally able to care for yourself (ECOG performance status 0 or 1).
- Your liver, kidney, and blood counts meet basic safety levels (your doctor will check these).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a combination of radiation therapy and two drugs (anlotinib and penpulimab) given before surgery for soft tissue sarcoma. The goal is to see if this approach can shrink tumors and improve outcomes.
This trial tests a precision medicine approach by giving targeted therapy before surgery for high-risk soft tissue sarcoma. The goal is to see if matching treatment to your tumor's type can improve outcomes.
This trial tests a newer way of giving radiation (spatially fractionated) compared to standard radiation for people with large soft tissue sarcomas. It aims to see if the new method works better.
This trial tests a new way of giving radiation therapy (called spatially fractionated radiotherapy) combined with a treatment strategy called PraG (pembrolizumab and granulocyte-macrophage colony-stimulating factor) for people with soft tissue sarcoma that cannot be removed or has spread. The goal is to see if the combination can help shrink or control the cancer.
This trial is testing a new combination of four treatments (an experimental drug, two chemo-like drugs, and radiation) for advanced soft tissue sarcoma that hasn't responded to earlier treatments. The goal is to see if this combination can help shrink or slow the cancer.
This study tests whether giving radiation, chemotherapy, and immunotherapy together can control high-risk soft tissue sarcoma that is hard to remove or may come back after surgery. It may help by attacking cancer in different ways, including boosting the immune system.
Hear when a new Soft Tissue Sarcoma (STS) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.