A study of LY4175408 for advanced cancer
Treatments studied
Part of Cancer, Lungs & breathing, Skin, Women’s health & pregnancy clinical trials.
This trial tests a new targeted drug (LY4175408) for people with certain advanced solid tumors (lung, endometrial, or triple negative breast cancer) who have already tried standard treatments. The goal is to see if the drug is safe and effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have one of these cancers: non-small cell lung cancer, small cell lung cancer, endometrial cancer, or triple negative breast cancer.
- You have tried all standard treatments for your cancer, or you are refusing the next best standard treatment, or there is no standard treatment available.
- You are able to take care of yourself (day-to-day activities) with little or no help (ECOG score of 0 or 1).
- If you are in certain groups, your tumor must be measurable on scans.
- You have not had a specific type of targeted therapy called a PTK7 antibody-drug conjugate (ADC) with a topoisomerase I inhibitor before.
- You do not have serious ongoing side effects from past treatments, uncontrolled brain metastases, active infections, heart problems, or a history of lung inflammation.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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