Study of LY4257496 for people with GRPR-positive solid tumors
Part of Cancer, Digestive system, Kidney & urinary, Skin, Women’s health & pregnancy clinical trials.
This trial tests a new drug, LY4257496, in people with certain types of cancer that have a protein called GRPR on their cells. The study aims to see if the drug can help shrink tumors or slow the cancer's growth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a cancer that has spread or cannot be removed by surgery
- Your cancer cells have a protein called GRPR, found by a special scan
- You have one of these cancer types: breast (ER+ with any HER2 status), esophageal, stomach, colorectal, prostate, endometrial (certain types), low-grade ovarian, or another solid tumor outside the brain (for certain study groups)
- You are able to get around and take care of yourself (ECOG performance status 0 or 1)
- You have not had certain prior radiation treatments or radiopharmaceutical therapy (some exceptions apply)
- You do not have uncontrolled infections like hepatitis B, C, HIV, or active pancreatitis
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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