Adding vasopressin to standard treatment for septic shock
Part of Infections clinical trials.
This trial tests whether adding vasopressin (a hormone that narrows blood vessels) to usual care can improve recovery in patients with septic shock (a severe infection causing very low blood pressure). If you are already on a strong blood pressure medication, this study may help stabilize your condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with septic shock (a life-threatening infection with very low blood pressure).
- You are currently receiving a medication called noradrenaline (a vasopressor) at a certain dose for less than 12 hours.
- Your heart function has been assessed and found to be appropriate for this therapy.
- You (or your family) have agreed to participate in this study.
- You must be affiliated with social security (in France).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether giving a second medicine called vasopressin early (along with norepinephrine) helps people with sepsis and low blood pressure better than waiting to use vasopressin only if norepinephrine doesn't work. It may improve blood pressure control and reduce the need for strong medicines.
This study observes how the medication vasopressin works when added to standard treatment for septic shock in the ICU. It helps doctors understand if vasopressin improves outcomes for patients with severe infection and low blood pressure.
This study compares giving vasopressin earlier vs. later to patients with septic shock who are already on norepinephrine. The goal is to see if adding vasopressin sooner helps improve blood pressure recovery.
This trial tests whether different blood pressure medicines protect kidney function better in people with septic shock (a severe infection that causes low blood pressure). It compares norepinephrine (the standard treatment) with other options to see which is best for the kidneys.
This study tests an investigational fluid called VBI-S to see if it can help raise blood pressure in people with septic shock who are not responding to standard fluids. You may qualify if you have severe infection and low blood pressure that needs medication support.
This trial compares two ways to safely stop the vasopressin medication in people with sepsis who are in the ICU. It aims to find the best approach to wean off this blood pressure support, which could help you recover more smoothly.
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