Testing lidocaine and steroids for headache after bleeding stroke
Treatments studied
Part of Brain & nervous system, Heart & circulation, Pain clinical trials.
This study tests whether giving two medicines (lidocaine and methylprednisolone) directly into the artery during a routine brain vessel procedure can help relieve headaches caused by a bleeding stroke. It may help find a new treatment for this type of headache.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and had a confirmed bleeding stroke (called a subarachnoid hemorrhage) seen on a scan.
- You will already be having a catheter-based brain vessel study (called a DSA) as part of your routine care.
- You have headaches that can be rated on a standard pain scale, and you are able to report your pain level.
- You are mentally alert enough to understand and sign a consent form.
- You are not allergic to lidocaine (or similar numbing drugs), egg/soy products, or methylprednisolone (a steroid).
- You do not have certain serious heart rhythm problems, uncontrolled diabetes, or are not pregnant/breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a numbing injection inside the nose to quickly relieve severe headaches caused by a brain bleed (subarachnoid hemorrhage). It may help reduce pain without strong medicines.
This trial tests whether giving a numbing medicine (lidocaine) and steroids into the artery that covers the brain can help reduce pain after a brain bleed. It may be an option for people with a specific type of bleeding who have not had certain brain surgeries or procedures.
This study tests whether a lidocaine infusion (given through an IV) can safely reduce severe headaches after a subarachnoid hemorrhage (a type of brain bleed). You may qualify if you had a spontaneous bleed and can communicate your pain level.
This study tests if a numbing spray applied inside the nose can help reduce headaches in people who have had a brain bleed from a ruptured aneurysm. The treatment targets a nerve cluster linked to headache pain.
This trial tests a procedure that uses a small camera to remove the blood clot from the brain, combined with a steroid medication, to reduce damage from a brain bleed. It may be an option for people with a moderate-to-large brain bleed in the outer part of the brain who can be treated within 24 hours.
This trial tests injecting lidocaine into a specific artery to treat severe migraines. It aims to see if this can stop headache pain that hasn't responded to other treatments.
Hear when a new Headaches Associated With Subarachnoid Hemorrhage (SAH) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.