Clin2
NCT07059221Likely a fitRecruiting

New drug combo for advanced head and neck cancer

Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Treatments studied

Part of Cancer clinical trials.

This trial tests a new combination of drugs (SHR-A2102 and Adebrelimab) with or without other anti-cancer therapies for head and neck cancer that has come back or spread. It aims to see if these treatments can shrink tumors or slow the disease.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
210 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You must have advanced or metastatic squamous cell carcinoma of the head and neck (excluding nasopharynx, sinuses, salivary glands, or skin origin).
  • You should be able to walk around and do light activity (ECOG 0 or 1).
  • You need at least one measurable tumor on scans (like CT or MRI).
  • You must be willing to use effective birth control during the trial (if you or your partner could become pregnant).
  • You cannot have certain other serious conditions like uncontrolled brain spread, severe lung disease, other active cancers, or serious infections.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06474468Recruiting· Phase 1/Phase 2
Study of a new drug combo for advanced esophageal cancer

This trial tests a combination of two investigational drugs for people with advanced or metastatic esophageal squamous cell carcinoma. The goal is to see if the combination can shrink tumors or slow cancer growth.

Jinan, Shandong
NCT06512051Recruiting· Phase 1/Phase 2
Study of SHR-A2102 and Adebrelimab for advanced lung cancer

This trial tests a combination of two drugs, SHR-A2102 and Adebrelimab, with or without other treatments, for people with advanced or metastatic non-small cell lung cancer that cannot be removed by surgery or cured with radiation. It aims to see if this approach can shrink tumors or slow the cancer's growth.

Beijing, Beijing Municipality
NCT06869473Recruiting· Phase 2
Cetuximab, chemo, and avelumab for head and neck cancer

This trial tests a combination of targeted therapy (cetuximab) and immunotherapy (avelumab) plus chemotherapy as a first treatment for people with head and neck cancer that has come back or spread. The goal is to see if adding these medicines helps control the cancer longer.

Cagliari, CAGLIARI
NCT07554768Not yet recruiting· Phase 2
Radiation plus immunotherapy for advanced head and neck cancer

This trial tests whether combining radiation therapy with immunotherapy works better than immunotherapy alone for advanced head and neck cancer that hasn't been treated before. The goal is to help your body's immune system fight the cancer more effectively.

Guangzhou, Guangdong
NCT07041437Not yet recruiting· Phase 2
SHR-A2102 plus other drugs for advanced breast cancer

This trial tests a new drug SHR-A2102 combined with other treatments for advanced or metastatic breast cancer. It aims to see if the combination is safe and effective.

Shanghai, Shanghai Municipality
NCT06417554Recruiting· Phase 1/Phase 2
Study of SHR-A2102 for advanced solid tumors

This trial is testing a new drug, SHR-A2102, either alone or with other treatments, for people with advanced solid tumors that have stopped responding to standard therapy. The goal is to see if it can shrink tumors or slow the cancer's growth.

Beijing, Beijing Municipality

Hear when a new Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.